Effects of Skin Lightening Cream Agents - Hydroquinone and Kojic Acid, on the Skin of Adult Female Experimental Rats.
Joshua Oladele OwolabiSunday Oluwaseyi FabiyiLola Adeola AdelakinMiriammillicent Chinenyenwa EkwerikePublished in: Clinical, cosmetic and investigational dermatology (2020)
The prominent expression of p65 in the sections indicated deleterious effects of hydroquinone. Kojic acid was not found to have deleterious effects. Aloe vera prevented extensive disruption of stratum corneum by hydroquinone. The use of hydroquinone in skin lightening creams might raise health concerns. Aloe vera could be protective against hydroquinone.