Children with SARS-CoV-2 in the National COVID Cohort Collaborative (N3C).
Blake MartinPeter E DeWittSeth RussellAdit AnandKatie Rebecca BradwellCarolyn BremerDavera GabrielAndrew T GirvinJanos G HajagosJulie A McMurryAndrew J NeumannEmily Rose PfaffAnita WaldenJacob T WooldridgeYun Jae YooJoseph SaltzKenneth GersingChristopher G ChuteMelissa A HaendelRichard A MoffittTellen D BennettPublished in: medRxiv : the preprint server for health sciences (2021)
In the largest U.S. SARS-CoV-2-positive pediatric cohort to date, we observed differences in demographics, pre-existing comorbidities, and initial vital sign and laboratory test values between severity subgroups. Taken together, these results suggest that early identification of children likely to progress to severe disease could be achieved using readily available data elements from the day of admission. Further work is needed to translate this knowledge into improved outcomes.