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EMPROVING outcomes: Evaluating the effect of an ultralung protective strategy for patients with ARDS treated with ECMO.

April A GrantAmit BadiyeChristina MehtaZiyue WuMichael KoernerRodrigo ViannaMatthias LoebeAli Ghodsizad
Published in: Journal of cardiac surgery (2020)
Failing to protect the lungs with a lung protective strategy such as the EMPROVE protocol after ECMO cannulation was associated with mortality. For every 1 mm Hg increase in the mean PIP, the odds of dying increased 1.4 times, and for every 1% increase in the mean FiO2 , the odds of dying increased 1.16 times. For lung rest to truly be effective, the lungs must be relieved of the burden of gas exchange.
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