Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial.

Bjørn Erik NeerlandRolf BusundRune HaaverstadJorunn L HelbostadSvein Aslak LandsverkIeva MartinaityteHilde Margrethe NorumJohan RæderGeir SelbaekMelanie R SimpsonElisabeth SkaarNils Kristian SkjærvoldEva SkovlundArjen Jc SlooterØyvind Sverre SvendsenTheis TønnessenAlexander WahbaHenrik ZetterbergTorgeir Bruun Wyller

Published in: BMJ open (2022)

NCT05029050.

Keyphrases

cognitive decline
minimally invasive
mild cognitive impairment
study protocol
randomized controlled trial
coronary artery bypass
heart failure
clinical trial
double blind
hip fracture
percutaneous coronary intervention