Amnioinfusion vs. standard management for the second trimester PPROM: a systematic review and meta-analysis of observational studies and RCTs.

Ebru Celik Abdullah Burak Yildiz Sebile Güler Çekiç Ceren Unal Işıl AyhanRauf MelekogluTugba Gursoy

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2023)

The efficacy of serial TA on early PPROM associated morbidity and mortality is not attested. Additional randomized control trials with adequate power are needed.

Keyphrases

double blind
open label
placebo controlled
phase iii
preterm birth
phase ii
clinical trial
randomized controlled trial
pregnant women