Optimal protamine-to-heparin dosing ratio for the prevention of bleeding complications in patients undergoing TAVR-A multicenter experience.

Baravan Al-KassouVerena VeulemansJasmin ShamekhiOliver MaierKerstin PiaydaTobias ZeusAdem AksoyAndreas ZietzerMax MeertensVictor MauriMarcel WeberJan-Malte SinningEberhard GrubeMatti AdamFarhad BakhtiarySebastian ZimmerStephan BaldusMalte KelmGeorg NickenigAlexander Sedaghat

Published in: Clinical cardiology (2022)

Full heparin antagonization resulted in significantly lower rates of life-threatening and major bleeding after TAVR as compared to partial heparin reversal. The occurrence of stroke and myocardial infarction was low and comparable between both groups.

Keyphrases

atrial fibrillation
venous thromboembolism
patients undergoing
growth factor
transcatheter aortic valve replacement
aortic valve
aortic stenosis
heart failure
risk assessment
left ventricular
risk factors
cross sectional
clinical trial