Prevalence and significance of HMGA2 expression in oesophageal adenocarcinoma.

Jeffrey K MitoAgoston T AgostonPaola Dal CinAmitabh Srivastava

Published in: Histopathology (2017)

Our data suggest that HMGA2 is regulated in EAC primarily through non-chromosomal-level alterations that lead to increased HMGA2 expression. HMGA2-positive EAC correlates with adverse pathological features and worse patient outcomes.

Keyphrases

poor prognosis
squamous cell carcinoma
risk factors
long non coding rna
electronic health record
big data
copy number
emergency department
machine learning
radiation therapy
gene expression
dna methylation
artificial intelligence
adverse drug