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Malaria Chemoprevention in the Postdischarge Management of Severe Anemia.

Titus K KwambaiAggrey DhabangiRichard IdroRobert OpokaVictoria WatsonSimon KariukiNickline A KuyaEric D OnyangoKephas OtienoAaron M SamuelsMeghna R DesaiMichael Boele van HensbroekDuolao WangChandy C JohnBjarne RobberstadKamija S PhiriFeiko O Ter Kuile
Published in: The New England journal of medicine (2020)
In areas with intense malaria transmission, 3 months of postdischarge malaria chemoprevention with monthly dihydroartemisinin-piperaquine in children who had recently received treatment for severe anemia prevented more deaths or readmissions for any reason after discharge than placebo. (Funded by the Research Council of Norway and the Centers for Disease Control and Prevention; ClinicalTrials.gov number, NCT02671175.).
Keyphrases
  • plasmodium falciparum
  • chronic kidney disease
  • early onset
  • iron deficiency
  • young adults
  • randomized controlled trial
  • combination therapy
  • clinical trial
  • open label
  • study protocol
  • smoking cessation