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Association between the Use of Suvorexant and Hip Fracture in Older Adults in Japan Using a Nationwide Administrative Claims Database: A Matched Case-Control Study.

Tomoyuki SaitoShuko NojiriTakatoshi KasaiYoshimune HiratsukaMuneaki IshijimaHiroyuki Daida
Published in: Drugs & aging (2023)
Using RWD in Japanese older adults, we showed that sleep therapy with suvorexant was not associated with an increased risk of hip fracture. The results provide evidence-based drug safety information for the selection of hypnotics for sleep disorders, which increase with age.
Keyphrases
  • hip fracture
  • physical activity
  • case control
  • sleep quality
  • adverse drug
  • health insurance
  • cross sectional
  • emergency department
  • health information
  • stem cells
  • drug induced
  • bone marrow