Diagnostic and prognostic value of a 7-panel mutation testing in thyroid nodules with indeterminate cytology: the SWEETMAC study.

Bénédicte ClarisseNicolas GoardonJustine LequesneDominique VaurRenaud CiappucciniAlexandra LeconteHervé MonpeyssenVirginie Saguet-RysanekBénédicte ClarisseAudrey Lasne-CardonFabrice MénégauxLaurence LeenhardtCamille Buffet

Published in: Endocrine (2020)

By increasing the overall risk of cancer from 16 to 67% in mutated nodules and by diminishing it to 9% in wild-type, this study confirms the relevance of the 7-panel mutation testing in the diagnostic of nodules with IC. Genetic testing, however, did not predict outcome in the cancer patient subgroup.

Keyphrases

wild type
papillary thyroid
randomized controlled trial
high grade
young adults
study protocol
ultrasound guided
open label