Knockdown of ERN1 disturbs the expression of phosphoserine aminotransferase 1 and related genes in glioblastoma cells.

Oleksandr H MinchenkoMyroslava Y SliusarYevgen P KhikhloOleh V HalkinYuliia M ViletskaOlena O KhitaDmytro O Minchenko

Published in: Archives of biochemistry and biophysics (2024)

Changes in the expression of phosphoserine aminotransferase 1 and other genes related to serine synthesis are mediated by diverse ERN1-dependent mechanisms and contributed to suppressed proliferation and enhanced invasiveness of ERN1 knockdown glioblastoma cell.

Keyphrases

poor prognosis
induced apoptosis
binding protein
signaling pathway
single cell
cell cycle arrest
cell therapy
long non coding rna
gene expression
cell death
mesenchymal stem cells
dna methylation
transcription factor
cell proliferation
drug induced