[Analysis of the functional role of polymorphism in the CDKN2B-AS1 gene GWAS-significant for primary open-angle glaucoma (an in-silico study)].

N V Eliseeva I V Ponomarenko Mikhail I Churnosov

Published in: Vestnik oftalmologii (2021)

Polymorphism of the CDKN2B-AS1 gene (rs1063192, rs7865618, rs2157719, rs944800, rs4977756) has significant regulatory potential and is associated with the expression and alternative splicing of genes, which possibly underlies its association with primary open-angle glaucoma.

Keyphrases

genome wide
genome wide identification
copy number
poor prognosis
transcription factor
gene expression
molecular docking
human health