Effectiveness of Botulinum Toxin on Hand Tremor Intensity and Upper Limb Function in Patients with Parkinson's Disease: Results of a Systematic Review.

Fariba Eslamian Neda DolatkhahLeila FallahFatemeh Jahanjoo Vahideh Toopchizadeh Mahnaz Talebi

Published in: Tremor and other hyperkinetic movements (New York, N.Y.) (2023)

Tremor treatment in Parkinson's-disease (PD) is challenging. Drugs effect is temporary, and surgery is critical management. This study reviews the Botulinum-toxin injection efficacy in hand tremor intensity and upper limb function. The results showed a decrease in unified Parkinson's disease rating scale (UPDRS)_20 and UPDRS_21 by 1.22 ± 1.1 and 1.20 ± 0.9, respectively, 6-16 weeks after injection.

Keyphrases

upper limb
botulinum toxin
deep brain stimulation
parkinson disease
randomized controlled trial
high intensity
atrial fibrillation
replacement therapy
drug induced