Identification of key genes in invasive clinically non-functioning pituitary adenoma by integrating analysis of DNA methylation and mRNA expression profiles.

Sen ChengWeiyan XieYazhou MiaoJing GuoJichao WangChuzhong LiYazhuo Zhang

Published in: Journal of translational medicine (2019)

The DNA methylation and expression levels of PHYHD1, LTBR, MYBPHL, C22orf42, PRR5, ANKDD1A, RAB13, CAMKV, KIFC3, WNT4 and STAT6 are associated with tumor invasion, and these genes may become the potential genes for targeted therapy.

Keyphrases

genome wide
dna methylation
bioinformatics analysis
gene expression
genome wide identification
cell proliferation
poor prognosis
stem cells
copy number
genome wide analysis
risk assessment
binding protein
long non coding rna
growth hormone