Frequency of Asymptomatic Optic Nerve Enhancement in 203 Patients With MOG Antibody-Associated Disease.
Deena A TajfirouzAjay A MadhavanJohann M Pacheco MarreroKarl N KreckeKalli J FautschEoin Patrick FlanaganSean J PittockShailee ShahM Tariq BhattiJohn J ChenPublished in: Neurology(R) neuroimmunology & neuroinflammation (2024)
Asymptomatic optic nerve enhancement occurred in 13% of interattack MRIs, the majority in patients with prior ON and occurring at prior sites of optic nerve enhancement. New asymptomatic optic nerve enhancement in areas without prior ON was rare. These findings are important for understanding the natural history of MOGAD, the interpretation of symptoms or response to treatment, and the adjudication of attacks in clinical trials.