Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4.

Irina VelikyanUlrika RosenströmRam K SelvarajuBarbro ErikssonIrina Velikyan

Published in: Acta diabetologica (2017)

IPR as well as the exocrine GLP-1R density is the main determinants of the species variability in pancreatic uptake. Thus, the IPR in human is an important factor for assessing the potential of GLP-1R as an imaging biomarker for pancreatic beta cells.

Keyphrases

induced apoptosis
endothelial cells
high resolution
genetic diversity
oxidative stress
signaling pathway
risk assessment
induced pluripotent stem cells
endoplasmic reticulum stress
pluripotent stem cells
photodynamic therapy
fluorescence imaging