Early Respiratory Bacterial Detection and Antistaphylococcal Antibiotic Prophylaxis in Young Children with Cystic Fibrosis.
Matthew N HurleyAndrew FogartyTricia M McKeeverChristopher H GossMargaret RosenfeldAlan Robert SmythPublished in: Annals of the American Thoracic Society (2019)
The risk of first detection of S. aureus and P. aeruginosa was greater in the United States than in the United Kingdom. In the United Kingdom, the risk of first P. aeruginosa detection was increased among those receiving flucloxacillin compared with those who received no prophylaxis. These observational findings should be examined in randomized controlled trials.