Effectiveness of combined targeted and hormonal therapies for post-menopausal women with hormone receptor-positive and HER2-negative advanced breast cancer: A systematic review and meta-analysis of RCTs.

Vitalis OkworChika Juliet OkworMaryjane Ukwuoma Martins Nweke

Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2024)

Compared with hormonal monotherapy, targeted plus hormonal therapy significantly improves PFS, OS and ORR in postmenopausal women with HR+/HER2- advanced breast cancer.

Keyphrases

polycystic ovary syndrome
cancer therapy
randomized controlled trial
breast cancer risk
systematic review
open label
insulin resistance
stem cells
drug delivery
metabolic syndrome
adipose tissue
skeletal muscle
bone marrow
replacement therapy