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Decoding Molecular Mechanisms Underlying Outcomes After Ischemic Stroke Thrombectomy by RNA Sequencing of Retrieved Clots.

Briana A SantoKerry E PoppenbergShiau-Sing CiecierskaJaims LimAmmad A BaigVinay JaikumarKunal P RaygorTatsat R PatelMunjal ShahElad I LevyAdnan H SiddiquiVincent M Tutino
Published in: Molecular diagnosis & therapy (2024)
Our study revealed a distinct gene expression pattern and dysregulated biological pathways associated with ENI. This expression pattern was also predictive of long-term outcome, suggesting a biological link between those ENIs and 90-day mRS.
Keyphrases
  • gene expression
  • single cell
  • poor prognosis
  • dna methylation
  • atrial fibrillation
  • acute ischemic stroke