Mesenchymal stromal cell secretory molecules improve the functional survival of human islets.

Tzu-Wen HongSara CaxariaLydia F Daniels GatwardSufyan HussainMin ZhaoAileen J F King Chloe L Rackham Peter M Jones

Published in: Diabetic medicine : a journal of the British Diabetic Association (2023)

Pre-treating human islets before transplantation with a defined cocktail of MSC-derived molecules could be employed to improve the quality of human islets for transplantation therapy for type 1 diabetes.

Keyphrases

endothelial cells
type diabetes
induced pluripotent stem cells
pluripotent stem cells
bone marrow
cell therapy
stem cells
cardiovascular disease
mesenchymal stem cells
single cell
skeletal muscle
free survival