Acute coronary syndrome is associated with a substantial change in the platelet lipidome.
Tobias HarmAlexander BildKristina DittrichAndreas GoldschmiedJeremy NesteleMadhumita ChatterjeeXiaoqing FuKyra KolbTatsiana CastorOliver BorstTobias GeislerDominik RathMichael LämmerhoferMeinrad Paul GawazPublished in: Cardiovascular research (2021)
Our results reveal that the platelet lipidome is altered in ACS and up-regulated lipids embody primarily glycerophospholipids. Alterations of the platelet lipidome, especially of medium chain lipids, may play a role in the pathophysiology of ACS.