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Acute coronary syndrome is associated with a substantial change in the platelet lipidome.

Tobias HarmAlexander BildKristina DittrichAndreas GoldschmiedJeremy NesteleMadhumita ChatterjeeXiaoqing FuKyra KolbTatsiana CastorOliver BorstTobias GeislerDominik RathMichael LämmerhoferMeinrad Paul Gawaz
Published in: Cardiovascular research (2021)
Our results reveal that the platelet lipidome is altered in ACS and up-regulated lipids embody primarily glycerophospholipids. Alterations of the platelet lipidome, especially of medium chain lipids, may play a role in the pathophysiology of ACS.
Keyphrases
  • acute coronary syndrome
  • percutaneous coronary intervention
  • antiplatelet therapy
  • transcription factor
  • fatty acid
  • genome wide
  • dna methylation
  • gene expression
  • atrial fibrillation