Evaluation of the anti-cancer efficacy of lipid nanoparticles containing siRNA against HPV16 E6/E7 combined with cisplatin in a xenograft model of cervical cancer.

Sung Wan KangOk-Ju KangJi-Young LeeHyejeong KimHunsoon JungHongjoong KimShin Wha LeeYong Man KimEun Kyung Choi

Published in: PloS one (2024)

The combination of ENB101-LNP, which inhibits E6/E7 of HPV 16, with cisplatin, demonstrated significant anticancer activity in the xenograft mouse model of cervical cancer.

Keyphrases

mouse model
high grade
cervical cancer screening
cancer therapy
fatty acid
drug delivery
walled carbon nanotubes