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Comparative efficacy of pharmacologic therapies for MASH in reducing liver fat content: Systematic review and network meta-analysis.

Benjamin KohJieling XiaoCheng Han NgMichelle LawShyna Zhuoying GunalanPojsakorn DanpanichkulVijay RamadossBenedix Kuan Loon SimEn Ying TanChong Boon TeoBenjamin NahMargaret TengKarn WijarnpreechaYuya SekoMei Chin LimHirokazu TakahashiAtsushi NakajimaMazen NoureddinMark MuthiahDaniel Q HuangStephen Caldwell
Published in: Hepatology (Baltimore, Md.) (2024)
This study provides an updated, relative rank-order efficacy of therapies for MASH in reducing hepatic fat. These data may help inform the design and sample size calculation of future clinical trials and assist in the selection of combination therapy.
Keyphrases
  • combination therapy
  • clinical trial
  • adipose tissue
  • fatty acid
  • electronic health record
  • current status
  • machine learning
  • phase ii
  • phase iii
  • placebo controlled