The CC Genotype of Insulin-Induced Gene 2 rs7566605 Is a Protective Factor of Hypercholesteremia Susceptible to Mild Cognitive Impairment, Especially to the Executive Function of Patients with Type 2 Diabetes Mellitus.
Haoqiang ZhangRong HuangSai TianKe AnWenwen ZhuJijing ShiWuyou CaoShaohua WangPublished in: BioMed research international (2020)
CC genotype of INSIG-2 rs7566605 may be a protective factor of hypercholesteremia susceptible to MCI, especially to the executive function of T2DM. This trial is registered with ChiCTROCC15006060.
Keyphrases
- mild cognitive impairment
- cognitive decline
- end stage renal disease
- ejection fraction
- type diabetes
- newly diagnosed
- chronic kidney disease
- clinical trial
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- high glucose
- copy number
- gene expression
- glycemic control
- phase iii
- endothelial cells
- skeletal muscle
- transcription factor
- insulin resistance
- stress induced