Inflammatory lobular hemangioma (T-cell-rich angiomatoid polypoid pseudolymphoma)-Assessment of FOS/FOSB and lymphoid markers and comparison with epithelioid hemangioma.

Ana Cristina VargasFiona M MacleanKwan Yee TsuLeanne MaDenis Moir

Published in: Journal of cutaneous pathology (2022)

We showed, based on FOS and/or FOSB immunohistochemical expression, that there is a possible link between ILH/TRAPP and epithelioid hemangioma/ALHE. The use of FOS and FOSB IHC in the routine diagnostic setting of cutaneous vascular lesions will help to redefine cases of ILH/TRAPP as a subset of these may represent inflammatory variants of epithelioid hemangioma.

Keyphrases

oxidative stress
poor prognosis
copy number
clinical practice
gene expression
binding protein
dna methylation
long non coding rna
clinical evaluation