A randomized controlled trial comparing perioperative vs. postoperative mFOLFOX6 for lower rectal cancer with suspected lateral pelvic lymph node metastasis (JCOG1310): a phase II/III randomized controlled trial.
Masayuki OhueSatoru IwasaJunki MizusawaYukihide KanemitsuManabu ShiozawaYusuke NishizawaHideki UenoKenji KatsumataMasayoshi YasuiShunsuke TsukamotoHiroshi KatayamaHaruhiko FukudaYasuhiro ShimadaPublished in: Japanese journal of clinical oncology (2022)
Perioperative mFOLFOX6 may be an insufficient treatment to improve survival of lower rectal cancer with lateral pelvic lymph node metastasis.
Keyphrases
- lymph node metastasis
- rectal cancer
- phase ii
- locally advanced
- patients undergoing
- phase ii study
- randomized controlled trial
- squamous cell carcinoma
- papillary thyroid
- clinical trial
- open label
- cardiac surgery
- phase iii
- study protocol
- minimally invasive
- metastatic colorectal cancer
- pulmonary embolism
- acute kidney injury
- placebo controlled
- double blind
- systematic review
- radiation therapy
- free survival
- smoking cessation