Neurocutaneous melanosis presenting with hydrocephalus and malignant transformation: case-based update.
Feras SharoufM ZabenA LammieP LeachM I BhattiPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2018)
Cutaneous manifestations of NCM are usually congenital, and neurological manifestations develop early in life. Patients with large or multiple congenital nevi should therefore be investigated early to facilitate treatment. MR imaging is the investigation of choice which can further assist in performing biopsy. Symptomatic NCM is refractory to radiotherapy and chemotherapy and has a poor prognosis. A multidisciplinary approach is necessary in the management of NCM patients.
Keyphrases
- poor prognosis
- long non coding rna
- end stage renal disease
- newly diagnosed
- ejection fraction
- locally advanced
- radiation therapy
- prognostic factors
- peritoneal dialysis
- computed tomography
- subarachnoid hemorrhage
- squamous cell carcinoma
- case report
- brain injury
- radiation induced
- mass spectrometry
- ultrasound guided
- rectal cancer
- contrast enhanced
- quality improvement
- decision making