Dextran-based priming solution during cardiopulmonary bypass attenuates renal tubular injury-A secondary analysis of randomized controlled trial in adult cardiac surgery patients.
Oscar KolsrudMikael BarbuGöran DellgrenKerstin BjörkAnna CorderfeldtAnders ThorenAnders JeppssonSven-Erik RickstenPublished in: Acta anaesthesiologica Scandinavica (2021)
In patients undergoing cardiac surgery with CPB, colloid-based priming solution (dextran 40) induced less renal tubular injury compared to a crystalloid-based priming solution. Whether a colloid-based priming solution will improve renal outcome in high-risk cardiac surgery, or not, needs to be evaluated in future studies on higher risk cardiac surgery patients.
Keyphrases
- cardiac surgery
- acute kidney injury
- end stage renal disease
- randomized controlled trial
- patients undergoing
- ejection fraction
- chronic kidney disease
- newly diagnosed
- high glucose
- prognostic factors
- clinical trial
- study protocol
- endothelial cells
- patient reported outcomes
- oxidative stress
- current status
- diabetic rats
- patient reported