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Oral octreotide capsules for acromegaly treatment: application of clinical trial insights to real-world use.

Maria FleseriuLisa B NachtigallSusan L SamsonShlomo Melmed
Published in: Expert review of endocrinology & metabolism (2024)
OOC are an option for patients with acromegaly including those who experience breakthrough symptoms, who have preference for oral therapies, or other reasons for declining injectable SRLs. OOC have been associated with improved patient-reported QoL measures compared with those reported for lanreotide and octreotide. Continued real-world experience will determine whether OOC, alone or in combination with other therapies, provides further advantages over current injectable acromegaly treatments.
Keyphrases
  • patient reported
  • clinical trial
  • growth hormone
  • neuroendocrine tumors
  • tissue engineering
  • double blind
  • study protocol
  • phase ii
  • randomized controlled trial
  • sleep quality
  • phase iii