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Fundamental bound on epidemic overshoot in the SIR model.

Maximilian M NguyenAri S FreedmanSinan A OzbaySimon Asher Levin
Published in: Journal of the Royal Society, Interface (2023)
We derive an exact upper bound on the epidemic overshoot for the Kermack-McKendrick SIR model. This maximal overshoot value of 0.2984 · · · occurs at [Formula: see text]. In considering the utility of the notion of overshoot, a rudimentary analysis of data from the first wave of the COVID-19 pandemic in Manaus, Brazil highlights the public health hazard posed by overshoot for epidemics with R 0 near 2. Using the general analysis framework presented within, we then consider more complex SIR models that incorporate vaccination.
Keyphrases
  • public health
  • electronic health record
  • machine learning
  • blood pressure
  • preterm infants
  • molecular dynamics
  • global health
  • preterm birth