Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer.
Takashi HirosawaMasaharu IshidaKentaro IshiiKeigo KaneharaKatsuyoshi KudoShinobu OhnumaTakashi KameiFuyuhiko MotoiTakeshi NaitohFlorin M SelaruMichiaki UnnoPublished in: PloS one (2018)
Our findings showed that genetic mutations are involved in BAP1 down-regulation, leading to promotion of the invasive character of cancer cells and poor prognosis in GBC.