A Molecularly Integrated Grade for Meningioma.
Joseph DriverSamantha E HoffmanSherwin TavakolEleanor WoodwardEduardo A MauryVarun BhaveNoah F GreenwaldFarshad NassiriKenneth D AldapeGelareh ZadehAbrar ChoudhuryHarish N VasudevanStephen T MagillDavid R RaleighMalak AbedalthagafiAyal A AizerBrian M AlexanderKeith L LigonDavid A ReardonPatrick Y WenOssama Al-MeftyAzra H LigonAdrian M DubucRameen BeroukhimElizabeth B ClausIan F DunnSandro SantagataWenya Linda BiPublished in: Neuro-oncology (2021)
We propose a molecularly integrated grading scheme for meningiomas that significantly improves upon the current WHO grading system in prediction of progression-free survival. This framework can be broadly adopted by clinicians with relative ease using widely available genomic technologies and presents an advance in the care of meningioma patients.