Prostate Specific Membrane Antigen Expression in a Syngeneic Breast Cancer Mouse Model.

Aditi A ShirkeJing WangGopolakrishnan RamamurthyArpan MahantyEthan WalkerLifang ZhangAbhiram PanigrahiXinning WangJames P Basilion

Published in: Molecular imaging and biology (2024)

The selective uptake of PSMA-1-Pc413 in these cancer tissues as well as the characterization and validation of PSMA expression on neovasculature in this syngeneic 4T1 model emphasizes their potential for advancements in targeted therapies and imaging techniques for BCa. PSMA holds great promise as an oncogenic target for BCa and its associated metastases.

Keyphrases

pet ct
pet imaging
poor prognosis
mouse model
prostate cancer
gene expression
high resolution
papillary thyroid
binding protein
transcription factor
long non coding rna
mass spectrometry
squamous cell
big data
risk assessment
benign prostatic hyperplasia
climate change
artificial intelligence
fluorescence imaging