A cofactor consumption screen identifies promising NfsB family nitroreductases for dinitrotoluene remediation.

Elsie M WilliamsAbigail V SharrockElizabeth L RylottNeil C BruceJoanna K MacKichanDavid F Ackerley

Published in: Biotechnology letters (2019)

Vibrio vulnificus NfsB is a particularly promising candidate for bioremediation applications, being ca. fivefold more catalytically efficient with 2,4-dinitrotoluene and over 26-fold more active with 2,6-dinitrotoluene than the benchmark E. coli nitroreductases NfsA and NfsB.

Keyphrases

escherichia coli
high throughput
biofilm formation
gene expression
staphylococcus aureus
pseudomonas aeruginosa