Baseline surveillance in Li Fraumeni syndrome using whole-body MRI: a systematic review and updated meta-analysis.
Maria Inez DacoregioPedro Cotta Abrahão ReisDavi Said Gonçalves CelsoLorena Escalante RomeroStephan AltmayerMaysa VilbertFabio Ynoe MoraesIsrael GomyPublished in: European radiology (2024)
Current evidence for whole-body MRI screening of asymptomatic Li-Fraumeni Syndrome (LFS) patients remains scarce. Whole-body MRI identified 41 out of 46 cancers at an early stage, achieving an overall detection rate of 6%. Whole-body MRI surveillance is a valuable method for detecting cancers in asymptomatic LFS patients.
Keyphrases
- diffusion weighted imaging
- contrast enhanced
- magnetic resonance imaging
- end stage renal disease
- early stage
- systematic review
- ejection fraction
- newly diagnosed
- chronic kidney disease
- public health
- peritoneal dialysis
- prognostic factors
- magnetic resonance
- computed tomography
- randomized controlled trial
- squamous cell carcinoma
- patient reported outcomes
- young adults
- case report
- patient reported
- lymph node
- loop mediated isothermal amplification
- rectal cancer
- case control