Hyperoxia speeds pulmonary oxygen uptake kinetics and increases critical power during supine cycling.

The present study determined the impact of hyperoxia on the phase II time constant of pulmonary oxygen uptake kinetics ( τ V ̇ O 2 ) and critical power (CP) during supine cycle exercise. Eight healthy men completed an incremental test to determine maximal oxygen uptake and the gas exchange threshold. Eight separate visits followed, whereby CP, τ V ̇ O 2 and absolute concentrations of oxyhaemoglobin ([HbO2 ]; via near-infrared spectroscopy) were determined via four constant-power tests to exhaustion, each repeated once in normoxia and once in hyperoxia (fraction of inspired O2  = 0.5). A 6 min bout of moderate-intensity exercise (70% of gas exchange threshold) was also undertaken before each severe-intensity bout, in both conditions. Critical power was greater (hyperoxia, 148 ± 29 W versus normoxia, 134 ± 27 W; P = 0.006) and the τ V ̇ O 2 reduced (hyperoxia, 33 ± 12 s versus normoxia, 52 ± 22 s, P = 0.007) during severe exercise in hyperoxia when compared with normoxia. Furthermore, [HbO2 ] was enhanced in hyperoxia compared with normoxia (hyperoxia, 67 ± 10 μm versus normoxia, 63 ± 11 μm; P = 0.020). The τ V ̇ O 2 was significantly related to CP in hyperoxia (R2  = 0.89, P < 0.001), but no relationship was observed in normoxia (r = 0.07, P = 0.68). Muscle oxygenation was increased, τ V ̇ O 2 reduced and CP increased in hyperoxia compared with normoxia, suggesting that τ V ̇ O 2 is an independent determinant of CP. The finding that τ V ̇ O 2 was related to CP in hyperoxia but not normoxia also supports this notion.