Decellularized Lung Extracellular Matrix Scaffold Promotes Human Embryonic Stem Cell Differentiation towards Alveolar Progenitors.

Afshin NooriMohammad Reza Mokhber DezfouliSareh RajabiFatemeh GanjiZahra GhezelayaghElie El AghaHossein BaharvandSirous Sadeghian ChaleshtoriYaser Tahamtani

Published in: Cell journal (2023)

Overall, our results suggest that dECM-derived scaffold improves the differentiation of DE cells towards lung alveolar progenitor cells in comparison with dECM-derived hydrogel and fibronectin-coated plates.

Keyphrases

extracellular matrix
tissue engineering
induced apoptosis
endothelial cells
cell cycle arrest
pluripotent stem cells
endoplasmic reticulum stress
oxidative stress
signaling pathway
wound healing
hyaluronic acid
cell proliferation
type iii
clinical evaluation