Human Wharton's jelly mesenchymal stem cells protect neural cells from oxidative stress through paracrine mechanisms.
Teresa Puig-PijuanMariana A de GodoyLuiza Rachel Pinheiro CarvalhoVictor Bodart-SantosRafael Soares LindosoPedro Moreno Pimentel-CoelhoRosália Mendez-OteroPublished in: Future science OA (2020)
WJ-MSCs have potential antioxidant and neuroprotective effects on hippocampal cultures which might be partially mediated by EVs.
Keyphrases
- mesenchymal stem cells
- umbilical cord
- oxidative stress
- endothelial cells
- cerebral ischemia
- bone marrow
- diabetic rats
- dna damage
- induced pluripotent stem cells
- ischemia reperfusion injury
- pluripotent stem cells
- cell therapy
- anti inflammatory
- induced apoptosis
- human health
- blood brain barrier
- stem cells
- brain injury
- signaling pathway
- climate change
- temporal lobe epilepsy