Protective role of 17β-estradiol in alcohol-associated liver fibrosis is mediated by suppression of integrin signaling.

Kruti NatarajMichael Schonfeld Adriana Rodriguez Irina Tikhanovich

Published in: Hepatology communications (2024)

Taken together, estrogen signaling protects mice from liver disease induced by a combination of alcohol and high-fat diet through upregulation of Prmt6 and suppression of integrin signaling.

Keyphrases

high fat diet
liver fibrosis
insulin resistance
adipose tissue
cell proliferation
metabolic syndrome
poor prognosis
alcohol consumption
high fat diet induced