Systematic review: duodenogastroesophageal (biliary) reflux prevalence, symptoms, oesophageal lesions and treatment.

Chamara BasnayakeAnnelies GeeraertsAns PauwelsGer KoekMichael VaeziTim Vanuytsel Tack Jan

Published in: Alimentary pharmacology & therapeutics (2021)

The prevalence of DGER increased with more advanced oesophageal lesions and did not explain persisting symptoms among patients taking PPI therapy. PPIs appear to be effective in the treatment of DGER. DGER remains an important consideration in patients with GERD and future therapies deserve more study.

Keyphrases

systematic review
risk factors
randomized controlled trial
depressive symptoms
physical activity
mesenchymal stem cells
small molecule
cell therapy
gastroesophageal reflux disease