Velopalatine and Bilateral Vocal Cord Paralysis Associated with Atezolizumab Treatment: A Severe and Previously Undocumented Side Effect in Cancer Immunotherapy.

Joan Lorente-PieraNatalia Díaz ZufiaurreSecundino Fernández-GonzálezJuan Alcalde

Published in: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India (2024)

Adverse effects of immunotherapeutic treatments like atezolizumab remain largely unknown due to limited experience. We present a 65-year-old man with sudden dyspnea and other symptoms, implicating immunotherapy. Prompt intervention and suspension were crucial. This study identifies a novel unreported adverse effect-bilateral vocal cord and velopalatine paralysis-associated with atezolizumab use.

Keyphrases

randomized controlled trial
genome wide
emergency department
sleep quality
combination therapy