The Effect of Furanocoumarin Derivatives on Induction of Apoptosis and Multidrug Resistance in Human Leukemic Cells.

Tomasz Piotr KubrakMarcin CzopPrzemysław KołodziejMarta Ziaja-SołtysJacek BoguckiAnna Makuch-KockaDavid AebisherJanusz KockiAnna Bogucka-Kocka

Published in: Molecules (Basel, Switzerland) (2019)

Our results clearly show that the furanocoumarin derivatives are therapeutic substances with antitumor activity inducing apoptosis in human leukemia cells with phenotypes of resistance.

Keyphrases

cell cycle arrest
induced apoptosis
endoplasmic reticulum stress
cell death
endothelial cells
oxidative stress
pi k akt
acute myeloid leukemia
induced pluripotent stem cells
pluripotent stem cells
cell proliferation