Comparative assessment of efficacy and safety of ambrisentan and bosentan in patients with pulmonary arterial hypertension: A meta-analysis.

Qinhua ZhaoNa GuoJun ChenDaniel ParksZhuang Tian

Published in: Journal of clinical pharmacy and therapeutics (2021)

The results of this network meta-analysis suggest that ambrisentan was similar to bosentan in efficacy, while it exhibited better tolerability with respect to abnormal liver function in comparison with bosentan, in patients with PAH.

Keyphrases

pulmonary arterial hypertension
systematic review
pulmonary artery
pulmonary hypertension
meta analyses
open label
randomized controlled trial
case control