Clinical and Molecular Findings after Autologous Stem Cell Transplantation or Cyclophosphamide for Scleroderma: Handling Missing Longitudinal Data.

Lynette Keyes-ElsteinAshley PinckneyEllen GoldmuntzBeverly WelchJennifer M FranksViktor MartyanovTammara A WoodLeslie CroffordMaureen D MayesPeter McSweeneyRichard NashGeorge GeorgesM E CsukaRobert SimmsDaniel E Furst Zsuzsanna H McMahanE William St ClairMichael L WhitfieldKeith M Sullivan

Published in: Arthritis care & research (2021)

Longitudinal trends estimated from two statistical models affirm the efficacy of HSCT over CYC in severe SSc. Failure to account for early loss of participants may distort estimated clinical trends over the long-term.

Keyphrases

stem cell transplantation
high dose
low dose
cross sectional
systemic sclerosis
early onset
rheumatoid arthritis
cell therapy
single molecule