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The N-terminal dimerization domains of human and Drosophila CTCF have similar functionality.

Sofia KamalyanOlga KyrchanovaNatalia KlimenkoValentin BaboshaYulia VasilevaElena BelovaDariya FursenkoOksana MaksimenkoPavel Georgiev
Published in: Epigenetics & chromatin (2024)
Our findings suggest that one of the evolutionarily conserved functions of the unstructured N-terminal dimerization domain is to recruit dCTCF to its genomic sites in vivo.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • transcription factor
  • copy number
  • pluripotent stem cells
  • dna methylation
  • genome wide