A novel role of astrocyte elevated gene-1 (AEG-1) in regulating nonalcoholic steatohepatitis (NASH).

Jyoti SrivastavaChadia L RobertsonKareem EbeidMikhail DozmorovDevaraja RajasekaranRachel MendozaAyesha SiddiqMaaged A AkielNidhi JariwalaXue-Ning ShenJolene J WindleMark A SublerNitai D MukhopadhyayShah GiashuddinShobha GhoshZhao LaiYidong ChenPaul B FisherAliasger K SalemArun J SanyalDevanand Sarkar

Published in: Hepatology (Baltimore, Md.) (2017)

AEG-1 might be a key molecule regulating initiation and progression of NASH. AEG-1 inhibitory strategies might be developed as a potential therapeutic intervention in NASH patients. (Hepatology 2017;66:466-480).

Keyphrases

end stage renal disease
randomized controlled trial
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
genome wide
copy number
transcription factor
patient reported
genome wide identification