Comparing the cumulative live birth rate of cleavage-stage versus blastocyst-stage embryo transfers between IVF cycles: a study protocol for a multicentre randomised controlled superiority trial (the ToF trial).

Simone CornelisseLiliana RamosBrigitte ArendsJanneke J Brink-van der VlugtJan Peter de BruinMax Hjn CurfsJosien DerhaagAngelique van DongenJannie van Echten-ArendsEva R GroenewoudJacques Wm MaasQuirine PieterseEvert Jp van SantbrinkEls SlappendelMaaike Af TraasJantien VisserCarlijn G VergouwHarold R VerhoeveLucette Aj van der WesterlakenYvonne WurthMoniek van der ZandenDidi Dm BraatMadelon van WelySebastiaan MastenbroekKathrin Fleischer

Published in: BMJ open (2021)

Netherlands Trial Register (NL 6857).

Keyphrases

study protocol
phase iii
clinical trial
phase ii
randomized controlled trial
open label
mass spectrometry
pregnancy outcomes