In-silico HMG-CoA reductase-inhibitory and in-vivo anti-lipidaemic/anticancer effects of carotenoids from Spondias mombin.
Damilohun Samuel MetibemuOluseyi Adeboye AkinloyeAdio Jamiu AkamoJude Ogechukwu OkoyeIdowu Olaposi OmotuyiPublished in: The Journal of pharmacy and pharmacology (2022)
Carotenoids from S. mombin demonstrate HMG-CoA reductase (HMGCR) inhibition, anti-lipidaemic, and anticancer effects. The inhibition of HMGCR by the carotenoids extract further poses it as a potential anti-hypercholesterolaemia compounds.
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