Diagnostic performance of molecular and serological tests of SARS-CoV-2 on well-characterised specimens from COVID-19 individuals: The EDCTP "PERFECT-study" protocol (RIA2020EF-3000).
Joseph FokamClaudia AlteriLuna ColagrossiAnne-Marie GenevieveDésiré TakouAlexis NdjoloVittorio ColizziNicaise NdembiCarlo-Federico PernoPublished in: PloS one (2022)
These efforts will contribute in creating the technical and clinical environment to facilitate earlier detection of Sars-CoV-2 in Africa in general and in Cameroon in particular. Specifically, the goals will be: (a) to implement technology transfer for capacity-building on conventional and point-of-care molecular assays, achieving a desirable performance for clinical diagnosis of SARS-CoV2; (b) to integrate/improve the available infrastructure, methodologies, and expertise on Sars-CoV2 detection; (c) to improve the turn-around-time for diagnosing COVID-19 infection with obvious advantage for patients/clinical management thanks to low-cost assays, thus permitting timely treatment and retention in care; (d) to assess the epidemiology of COVID-19 and circulating-variants in Cameroon as compared to strains found in other countries.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- low cost
- study protocol
- healthcare
- randomized controlled trial
- newly diagnosed
- high throughput
- ejection fraction
- escherichia coli
- clinical trial
- palliative care
- quality improvement
- label free
- risk factors
- real time pcr
- patient reported outcomes
- prognostic factors
- single molecule
- copy number
- gene expression
- open label
- chronic pain
- pain management
- fine needle aspiration