The efficacy of statins in the treatment of Alzheimer's disease: a meta-analysis of randomized controlled trial.

Kun XuanTianming ZhaoGuangbo QuHaixia LiuXin ChenYehuan Sun

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2020)

Statins used in AD patients had beneficial effects on the scores of MMSE scale in the short term (≤ 12 months), and statins could slow the deterioration of neuropsychiatric status and significantly improve activities of daily living ability in AD patients, but statins did not show an advantage in the change of the ADAS-Cog scale scores.

Keyphrases

end stage renal disease
randomized controlled trial
cardiovascular disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
type diabetes
study protocol
patient reported outcomes
smoking cessation
replacement therapy